MFSD2B antibody (Center)

Catalog No. ABIN783765

Product Details anti-MFSD2B Antibody

Target: MFSD2B (Major Facilitator Superfamily Domain Containing 2B (MFSD2B))

Binding Specificity: Center

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MFSD2B antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects MFSD2B at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the center of human MFSD2B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for MFSD2B

Target: MFSD2B (Major Facilitator Superfamily Domain Containing 2B (MFSD2B))

Alternative Name: MFSD2B (MFSD2B Products)

Synonyms: RGD1561716 antibody, Gm1964 antibody, major facilitator superfamily domain containing 2B antibody, MFSD2B antibody, Mfsd2b antibody

Background: Multidrug transporters, such as MFSD2B, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2B is closely related to MFSD2A, which is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting, playing a major role in the induction of MFSD2A expression during adaptive thermogenesis. Unlike MFSD2A, MFSD2B is expressed in few tissues and at relatively low levels, and is not induced during fasting, suggesting that MFSD2B may play other roles.

Gene ID: 388931

NCBI Accession: NP_001073942

UniProt: A6NFX1