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PAPPA2 antibody (N-Term)
PAPPA2
Reactivity: Human, Rat, Mouse
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PAPPA2 Antibody
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Target
See all PAPPA2 Antibodies
PAPPA2
(Pappalysin 2 (PAPPA2))
Binding Specificity
All epitopes for PAPPA2 antibodies
N-Term
Reactivity
All reactivities for PAPPA2 antibodies
Human, Rat, Mouse
Host
All hosts for PAPPA2 antibodies
Rabbit
Clonality
All clonalities for PAPPA2 antibodies
Polyclonal
Conjugate
All conjugates for PAPPA2 antibodies
This PAPPA2 antibody is un-conjugated
Application
All applications for PAPPA2 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects Pappalysin-2 / PAPPA2 at N-term.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Affinity chromatography purified via peptide column
Immunogen
15 amino acid peptide near the amino terminus of human PLAC3
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Discover our top product PAPPA2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target Details for PAPPA2
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Target
PAPPA2
(Pappalysin 2 (PAPPA2))
Alternative Name
Pappalysin-2 / PAPPA2 (PAPPA2 Products )
Synonyms
PAPP-A2 antibody, PLAC3 antibody, Pappe antibody, PAPP-E antibody, PAPPE antibody, si:dkey-39f8.1 antibody, pappalysin 2 antibody, Pappa2 antibody, PAPPA2 antibody, pappa2 antibody
Background
PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.Synonyms: PAPP-A2, PAPP-E, PLAC3, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1
Gene ID
60676
NCBI Accession
NP_064714
UniProt
Q9BXP8
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