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Axin antibody (C-Term)
AXIN1
Reactivity: Human, Mouse, Rat
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Axin Antibody
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Target
See all Axin (AXIN1) Antibodies
Axin (AXIN1)
(Axin 1 (AXIN1))
Binding Specificity
All epitopes for Axin antibodies
C-Term
Reactivity
All reactivities for Axin antibodies
Human, Mouse, Rat
Host
All hosts for Axin antibodies
Rabbit
Clonality
All clonalities for Axin antibodies
Polyclonal
Conjugate
All conjugates for Axin antibodies
This Axin antibody is un-conjugated
Application
All applications for Axin antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects Axin-1 at C-term.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Affinity chromatography purified via peptide column
Immunogen
14 amino acid peptide near the carboxy terminus of human AXIN1
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Discover our top product AXIN1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
14 amino acid peptide near the carboxy terminus of human AXIN1
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target Details for Axin
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Target
Axin (AXIN1)
(Axin 1 (AXIN1))
Alternative Name
Axin-1 (AXIN1 Products )
Synonyms
AXIN1 antibody, axin antibody, fused antibody, xAxin antibody, LOC100226467 antibody, AXIN antibody, PPP1R49 antibody, AI316800 antibody, Axin antibody, Fu antibody, Kb antibody, Ki antibody, kinky antibody, knobbly antibody, AXIN1-RGS antibody, wu:fi22e03 antibody, wu:fj14c08 antibody, wu:fk11b03 antibody, zgc:109872 antibody, axin 1 antibody, axin 1 S homeolog antibody, axin 1 L homeolog antibody, AXIN1 antibody, axin1.S antibody, axin1.L antibody, Axin1 antibody, axin1 antibody
Background
AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), b-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of b-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.Synonyms: AXIN, AXIN1, Axis inhibition protein 1
Gene ID
8312
NCBI Accession
NP_003493
UniProt
O15169
Pathways
WNT Signaling , Sensory Perception of Sound , Regulation of G-Protein Coupled Receptor Protein Signaling
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