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KPNA3 antibody (C-Term)
KPNA3
Reactivity: Human, Mouse, Rat
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-KPNA3 Antibody
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Target
See all KPNA3 Antibodies
KPNA3
(Karyopherin alpha 3 (Importin alpha 4) (KPNA3))
Binding Specificity
All epitopes for KPNA3 antibodies
C-Term
Reactivity
All reactivities for KPNA3 antibodies
Human, Mouse, Rat
Host
All hosts for KPNA3 antibodies
Rabbit
Clonality
All clonalities for KPNA3 antibodies
Polyclonal
Conjugate
All conjugates for KPNA3 antibodies
This KPNA3 antibody is un-conjugated
Application
All applications for KPNA3 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects KPNA3 / Importin alpha-3 at C-term.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Affinity chromatography purified via peptide column
Immunogen
14 amino acid peptide near the carboxy end of human KPNA3
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Discover our top product KPNA3 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target Details for KPNA3
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Target
KPNA3
(Karyopherin alpha 3 (Importin alpha 4) (KPNA3))
Alternative Name
KPNA3 / Importin alpha-3 (KPNA3 Products )
Synonyms
IPOA4 antibody, si:dz79f24.2 antibody, importin antibody, SRP1 antibody, SRP1gamma antibody, SRP4 antibody, hSRP1 antibody, ipoa4 antibody, srp1 antibody, srp1gamma antibody, srp4 antibody, karyopherin (importin) alpha 3 antibody, karyopherin alpha 3 (importin alpha 4) antibody, karyopherin subunit alpha 3 antibody, karyopherin alpha 3 (importin alpha 4) L homeolog antibody, Kpna3 antibody, kpna3 antibody, KPNA3 antibody, kpna3.L antibody
Background
Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA3, the alpha subunit 3 of karyopherin, is silimar to human KPNA2, suggesting that KPNA3 may be involved in the nuclear transport system. It is ubiquitously expressed and recent studies have shown that human KPNA3 may be associated with schizophrenia.Synonyms: Importin alpha Q2, Karyopherin subunit alpha-3, QIP2, SRP1-gamma
Gene ID
3839
NCBI Accession
NP_002258
UniProt
O00505
Pathways
Protein targeting to Nucleus
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