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KPNA4 antibody (N-Term)
KPNA4
Reactivity: Human, Mouse, Rat
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-KPNA4 Antibody
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Target
See all KPNA4 Antibodies
KPNA4
(Karyopherin (Importin) alpha 4 (KPNA4))
Binding Specificity
All epitopes for KPNA4 antibodies
N-Term
Reactivity
All reactivities for KPNA4 antibodies
Human, Mouse, Rat
Host
All hosts for KPNA4 antibodies
Rabbit
Clonality
All clonalities for KPNA4 antibodies
Polyclonal
Conjugate
All conjugates for KPNA4 antibodies
This KPNA4 antibody is un-conjugated
Application
All applications for KPNA4 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects KPNA4 / Importin alpha-4 at N-term.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Affinity chromatography purified via peptide column
Immunogen
15 amino acid peptide near the amino terminus of human KPNA4
Top Product
Discover our top product KPNA4 Primary Antibody
Alternatives
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anti-Karyopherin (Importin) alpha 4 (KPNA4) (AA 38-87) antibody
KPNA4
Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Hamster, Monkey, Bat
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target Details for KPNA4
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Target
KPNA4
(Karyopherin (Importin) alpha 4 (KPNA4))
Alternative Name
KPNA4 / Importin alpha-4 (KPNA4 Products )
Synonyms
IPOA3 antibody, QIP1 antibody, SRP3 antibody, 6 antibody, ATIMPALPHA3 antibody, IMPA-3 antibody, IMPORTIN ALPHA 3 antibody, IMPORTIN ALPHA ISOFORM 3 antibody, MODIFIER OF SNC1 antibody, T10M13.16 antibody, T10M13_16 antibody, LOC100224013 antibody, 1110058D08Rik antibody, importin antibody, ipoa3 antibody, qip1 antibody, srp3 antibody, impa3 antibody, wu:fa56d07 antibody, wu:fa66g10 antibody, wu:fe14c04 antibody, wu:fi04h11 antibody, wu:fi19b05 antibody, karyopherin subunit alpha 4 antibody, ARM repeat superfamily protein antibody, importin alpha 3 antibody, karyopherin (importin) alpha 4 antibody, karyopherin alpha 4 (importin alpha 3) S homeolog antibody, karyopherin alpha 4 (importin alpha 3) antibody, KPNA4 antibody, MOS6 antibody, LOC100533341 antibody, Kpna4 antibody, kpna4.S antibody, kpna4 antibody
Background
Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. Molecules containing the classical nuclear localization signal (NLS) are transported into the nucleus by alpha/beta heterodimers. KPNA3 has been shown to be important in the TNF-alpha-induced nuclear import of NF-kappaB. It is also involved in the stress-mediated nuclear stabilization of p53 and the nuclear import and replication of HIV-1 in both dividing and non-dividing cells.Synonyms: Importin alpha Q1, Karyopherin subunit alpha-4, QIP1
Gene ID
3840
NCBI Accession
NP_002259
UniProt
O00629
Pathways
Protein targeting to Nucleus
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