NLRC5 antibody (N-Term)

Catalog No. ABIN783699

Product Details anti-NLRC5 Antibody

Target: NLRC5 (NLR Family, CARD Domain Containing 5 (NLRC5))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRC5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: This antibody detects NOD4 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the amino terminus of human NOD4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for NLRC5

Target: NLRC5 (NLR Family, CARD Domain Containing 5 (NLRC5))

Alternative Name: NOD4 (NLRC5 Products)

Synonyms: NOD4 antibody, CLR16.1 antibody, NOD27 antibody, AI451557 antibody, AK220210 antibody, NLR family CARD domain containing 5 antibody, NLR family, CARD domain containing 5 antibody, NLRC5 antibody, nlrc5 antibody, Nlrc5 antibody

Background: NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-?B and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.Synonyms: CLR16.1, FLJ21709, FLJ39711, NLRC5, NOD27, NOD4

Gene ID: 84166

NCBI Accession: NP_115582

UniProt: Q86WI3