SESTD1 antibody (C-Term)

Catalog No. ABIN783683

Product Details anti-SESTD1 Antibody

Target: SESTD1 (SEC14 and Spectrin Domains 1 (SESTD1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SESTD1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects SESTD1 / SOLO at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human SESTD1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for SESTD1

Target: SESTD1 (SEC14 and Spectrin Domains 1 (SESTD1))

Alternative Name: SESTD1 / SOLO (SESTD1 Products)

Synonyms: SOLO antibody, 1500031J16Rik antibody, A930010O20 antibody, Solo/Trio8 antibody, RGD1562244 antibody, sestd1-A antibody, SEC14 and spectrin domain containing 1 antibody, SEC14 and spectrin domains 1 antibody, SEC14 and spectrin domain containing 1 S homeolog antibody, SESTD1 antibody, sestd1 antibody, Sestd1 antibody, sestd1.S antibody

Background: SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1,4,5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.Synonyms: Huntingtin-interacting protein-like protein, SEC14 domain and spectrin repeat-containing protein 1

Gene ID: 91404

NCBI Accession: NP_835224

UniProt: Q86VW0