Secernin 3 antibody (Center)

Catalog No. ABIN783657

Product Details anti-Secernin 3 Antibody

Target: Secernin 3 (SCRN3)

Binding Specificity: Center

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Secernin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: This antibody detects SCRN3. This antibody is predicted to not cross-react with other SCRN members. At least four isoforms of SCRN3 are known to exist, this antibody will recognize all four.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the center of human SCRN3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for Secernin 3

Target: Secernin 3 (SCRN3)

Alternative Name: Secernin-3 (SCRN3) (SCRN3 Products)

Synonyms: 4833415E20Rik antibody, AI427019 antibody, AV002033 antibody, Ses3 antibody, SES3 antibody, wu:fd60b06 antibody, zgc:55430 antibody, secernin 3 antibody, secernin 3 L homeolog antibody, Scrn3 antibody, SCRN3 antibody, scrn3 antibody, scrn3.L antibody

Background: SCRN3 is a member of the secernin family of proteins which includes the homologous SCRN1, a protein that was first identified as being involved in the regulation of exocytosis from peritoneal mast cells. Little is known of SCRN3, but studies have shown that SCRN1 may possess epitopes that function as tumor-associated antigens in gastric cancers and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN3 may also be involved in protein secretion or the regulation of cell growth.

Gene ID: 79634

NCBI Accession: NP_001180457

UniProt: Q0VDG4