SCUBE1 antibody (Center)

Catalog No. ABIN783649

Product Details anti-SCUBE1 Antibody

Target: SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCUBE1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the center of human SCUBE1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: 14 amino acid peptide near the center of human SCUBE1

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for SCUBE1

Target: SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))

Alternative Name: SCUBE1 (SCUBE1 Products)

Synonyms: 7330410C13Rik antibody, A630023E24Rik antibody, signal peptide, CUB domain and EGF like domain containing 1 antibody, signal peptide, CUB domain, EGF-like 1 antibody, SCUBE1 antibody, Scube1 antibody

Background: SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity, genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.Synonyms: Signal peptide CUB and EGF-like domain-containing protein 1

Gene ID: 80274

NCBI Accession: NP_766638

UniProt: Q8IWY4