FREM1 antibody (C-Term)

Catalog No. ABIN783634

Product Details anti-FREM1 Antibody

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FREM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: This antibody rescts with Muman and Mouse FREM1 and is predicted to not cross-react with other FRAS members.

Purification: Affinity Chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of Human FREM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FREM1

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Alternative Name: FREM1 (FREM1 Products)

Synonyms: BNAR antibody, C9orf143 antibody, C9orf145 antibody, C9orf154 antibody, MOTA antibody, TILRR antibody, TRIGNO2 antibody, RGD1306981 antibody, BC037594 antibody, D430009N09 antibody, D630008K06 antibody, eye antibody, eyes2 antibody, heb antibody, qbrick antibody, FRAS1 related extracellular matrix 1 antibody, Fras1 related extracellular matrix 1 antibody, Fras1 related extracellular matrix protein 1 antibody, FREM1 antibody, Frem1 antibody

Background: FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.Synonyms: C9orf143, C9orf145, C9orf154, FRAS1-related extracellular matrix protein 1, Protein QBRICK

Gene ID: 158326

NCBI Accession: NP_001171175

UniProt: Q5H8C1