TMEM88 antibody (C-Term)

Catalog No. ABIN783510

Product Details anti-TMEM88 Antibody

Target: TMEM88 (Transmembrane Protein 88 (TMEM88))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM88 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects TMEM88 / TMEM88A at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the carboxy terminus of human TMEM88

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for TMEM88

Target: TMEM88 (Transmembrane Protein 88 (TMEM88))

Abstract: TMEM88 Products

Synonyms: 2600017H02Rik antibody, RGD1561781 antibody, zgc:77242 antibody, transmembrane protein 88 antibody, transmembrane protein 88B antibody, transmembrane protein 88 a antibody, Tmem88 antibody, TMEM88 antibody, TMEM88B antibody, tmem88 antibody, tmem88a antibody

Background: Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.Synonyms: Transmembrane protein 88

Gene ID: 92162

NCBI Accession: NP_981956

UniProt: Q6PEY1