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AP3B2 antibody (N-Term)
AP3B2
Reactivity: Human, Mouse, Rat
WB, IF, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-AP3B2 Antibody
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Target
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AP3B2
(Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))
Binding Specificity
All epitopes for AP3B2 antibodies
N-Term
Reactivity
Human, Mouse, Rat
Host
All hosts for AP3B2 antibodies
Rabbit
Clonality
All clonalities for AP3B2 antibodies
Polyclonal
Conjugate
All conjugates for AP3B2 antibodies
This AP3B2 antibody is un-conjugated
Application
All applications for AP3B2 antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody detects AP3 complex subunit beta-2 (N-term).
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Affinity chromatography purified via peptide column
Immunogen
Raised against an 18 amino acid peptide near the amino terminus of human AP3B2
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for AP3B2
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Target
AP3B2
(Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))
Alternative Name
AP3 Complex Subunit beta-2 (AP3B2 Products )
Synonyms
AP3B2 antibody, DDBDRAFT_0217414 antibody, DDBDRAFT_0238781 antibody, DDB_0217414 antibody, DDB_0238781 antibody, NAPTB antibody, AI549966 antibody, AU042881 antibody, Naptb antibody, [b]-NAP antibody, beta-NAP antibody, beta3B antibody, adaptor related protein complex 3 beta 2 subunit S homeolog antibody, adaptor related protein complex 3 beta 2 subunit antibody, beta adaptin antibody, adaptor-related protein complex 3, beta 2 subunit antibody, ap3b2.S antibody, AP3B2 antibody, ap3b-2 antibody, ap3b2 antibody, Ap3b2 antibody
Background
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.Synonyms: AP-3 complex beta-2 subunit, AP3B2, Adapter-related protein complex 3 subunit beta-2, Adaptor protein complex AP-3 beta-2 subunit, Beta 3B Adaptin, Clathrin assembly protein complex 3 beta-2 large chain, Neuron-specific vesicle coat protein beta-NAP, beta-NAP
Gene ID
8120
NCBI Accession
NP_004635
UniProt
Q13367
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