TYW3 antibody (Center)

Catalog No. ABIN783490

Product Details anti-TYW3 Antibody

Target: TYW3 (tRNA-YW Synthesizing Protein 3 Homolog (TYW3))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYW3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects TYW3 at Center. TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist, this antibody will detect both isoforms.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the center of human TYW3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for TYW3

Target: TYW3 (tRNA-YW Synthesizing Protein 3 Homolog (TYW3))

Alternative Name: TYW3 (TYW3 Products)

Synonyms: C1orf171 antibody, 5230400J09Rik antibody, tRNA-yW synthesizing protein 3 homolog L homeolog antibody, tRNA-yW synthesizing protein 3 homolog antibody, tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) antibody, tyw3.L antibody, TYW3 antibody, Tyw3 antibody

Background: TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.Synonyms: C1orf171, tRNA wybutosine-synthesizing protein 3 homolog, tRNA-yW-synthesizing protein 3

Gene ID: 127253

NCBI Accession: NP_612476

UniProt: Q6IPR3