NKX3-2 antibody (Center)
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- Target See all NKX3-2 Antibodies
- NKX3-2 (NK3 Homeobox 2 (NKX3-2))
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Binding Specificity
- Center
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NKX3-2 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects BAPX1 / NKX3B at Center. BAPX1 antibody is predicted not to cross-react with other NKX homeobox proteins.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 19 amino acid peptide near the center of human BAPX1
- Top Product
- Discover our top product NKX3-2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Target
- NKX3-2 (NK3 Homeobox 2 (NKX3-2))
- Alternative Name
- BAPX1 / NKX3B (NKX3-2 Products)
- Synonyms
- bapx1 antibody, Xbap antibody, bapx1-A antibody, nkx3.2 antibody, BAPX1 antibody, NKX-3.2 antibody, NKX3.2 antibody, NKX3B antibody, SMMD antibody, Bapx1 antibody, Nkx-3.2 antibody, NK3 homeobox 2 antibody, NK3 homeobox 2 S homeolog antibody, NKX3-2 antibody, nkx3.2 antibody, nkx3-2.S antibody, Nkx3-2 antibody
- Background
- BAPX1 is the mammalian homolog of the Drosophila bagpipe homeobox gene and is expressed in the splanchnic mesoderm and embryonic skeleton. It is one of the earliest developmental markers for the sclerotome portion of the somite and the gut mesentery. BAPX1 is required for normal skeletal development, homozygous inactivating mutations in the BAPX1 gene result in spodylo-megaepiphyseal-metaphyseal dysplasia (SMMD). It has also been suggested to play a role in the proper development of the mammalian gut and is required for distal stomach development as part of a BARX1-dependent pathway.Synonyms: Bagpipe homeobox protein homolog 1, Homeobox protein NK-3 homolog B, Homeobox protein Nkx-3.2, NKX3-2, Nkx-3.2
- Gene ID
- 579
- NCBI Accession
- NP_001180
- UniProt
- P78367
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