VPS39 antibody (C-Term)

Catalog No. ABIN783395

Product Details anti-VPS39 Antibody

Target: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS39 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects VPS39 / VAM6 at C-term. At least four isoforms of VPS39 are known to exist, this antibody will detect all four. VPS39 antibody is predicted not to cross-react with TRAP1.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the carboxy terminus of human VPS39

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for VPS39

Target: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Alternative Name: VPS39 (VPS39 Products)

Synonyms: lbk antibody, vam6 antibody, DKFZp469J2314 antibody, A230065P22Rik antibody, AW743070 antibody, Vam6 antibody, Vam6P antibody, mVam6 antibody, TLP antibody, VAM6 antibody, hVam6p antibody, VPS39, HOPS complex subunit antibody, vacuolar protein sorting 39 homolog (S. cerevisiae) antibody, vam6/Vps39-like protein antibody, vacuolar protein sorting 39 antibody, VPS39 HOPS complex subunit antibody, VPS39 antibody, vps39 antibody, LOC100196283 antibody, NAEGRDRAFT_59276 antibody, Vps39 antibody

Background: VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-b response by coupling the TGF-b receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6.5.Synonyms: KIAA0770, VAM6, Vam6/Vps39-like protein

Gene ID: 23339

NCBI Accession: NP_056104

UniProt: Q96JC1

Pathways: SARS-CoV-2 Protein Interactome