ZBTB7A antibody (N-Term)

Catalog No. ABIN783361

Product Details anti-ZBTB7A Antibody

Target: ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB7A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ZBTB7A at N-term. At least two isoforms of ZBTB7A are known to exist, this antibody will recognize both isoforms. This antibody is predicted not to cross-react with other ZBTB protein family members.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the amino terminus of Human ZBTB7A

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ZBTB7A

Target: ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))

Alternative Name: ZBTB7A / Pokemon (ZBTB7A Products)

Synonyms: ZBTB7A antibody, FBI-1 antibody, FBI1 antibody, LRF antibody, ZBTB7 antibody, ZNF857A antibody, pokemon antibody, 9030619K07Rik antibody, 9130006G12Rik antibody, AI452336 antibody, Lrf antibody, Pokemon antibody, Zbtb7 antibody, OCZF antibody, zinc finger and BTB domain containing 7A antibody, zinc finger and BTB domain containing 7C antibody, zinc finger and BTB domain containing 7a antibody, ZBTB7A antibody, ZBTB7C antibody, Zbtb7a antibody

Background: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB7A, also known as LRF, was initially identified as a potential target of the LAZ-3/BCL-6 oncogene. Later reports demonstrated that it could bind to the wild-type IST (inducer of short transcripts) elements of HIV-1 long terminal repeats (LTRs) and stimulate Tat activity on the HIV-1 LTR. More recently it ZBTB7A has been recognized as a proto-oncogene whose overexpression contributes to malignancy in breast cancer and functions as a co-repressor of the androgen receptor in prostate cancer cells.Synonyms: FBI-1, FBI1, Factor binding IST protein 1, LRF, Leukemia/lymphoma-related factor, POK (POZ and Krueppel) erythroid myeloid ontogenic factor, TIP21, TTF-I-interacting peptide 21, ZBTB7, Zinc finger and BTB domain-containing protein 7A

Gene ID: 51341

NCBI Accession: NP_056982

UniProt: O95365