WIZ antibody (C-Term)

Catalog No. ABIN783351

Product Details anti-WIZ Antibody

Target: WIZ (ZNF803) (Zinc Finger Protein 803 (ZNF803))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIZ antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects WIZ / ZNF803 at C-term. At least four isoforms of WIZ are known to exist, this antibody will detect all four.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human TFF3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for WIZ

Target: WIZ (ZNF803) (Zinc Finger Protein 803 (ZNF803))

Alternative Name: WIZ / ZNF803 (ZNF803 Products)

Synonyms: ZNF803 antibody, widely-interspaced zinc finger motifs antibody, widely interspaced zinc finger motifs antibody, Wiz antibody, WIZ antibody

Background: WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its message was found to be expressed in the granule cell layers of the cerebellum as well as in the dentate gyrus and olfactory bulb. Later analysis indicates however that WIZ is ubiquitously expressed. WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. WIZ can also associate with CtBP family proteins, known to be transcriptional co-repressors, and has been suggested to link G9a/GLP complexes to the CtBP co-repressor machinery, possibly regulating complex stability and gene silencing.Synonyms: Widely-interspaced zinc finger-containing protein, Zinc finger protein 803

Gene ID: 58525

NCBI Accession: NP_067064

UniProt: O95785