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MAG antibody (AA 119-209)
MAG
Reactivity: Human
WB, IHC (p), EIA
Host: Mouse
Monoclonal
3C7
unconjugated
Product Details anti-MAG Antibody
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Target
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MAG
(Myelin Associated Glycoprotein (MAG))
Binding Specificity
All epitopes for MAG antibodies
AA 119-209
Reactivity
All reactivities for MAG antibodies
Human
Host
All hosts for MAG antibodies
Mouse
Clonality
All clonalities for MAG antibodies
Monoclonal
Conjugate
All conjugates for MAG antibodies
This MAG antibody is un-conjugated
Application
All applications for MAG antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to MAG.
Purification
Affinity chromatography on Protein A
Immunogen
MAG antibody was raised against mAG (NP_002352, 119 a.a. ~ 209 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Clone
3C7
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0,24 mg/mL
Buffer
PBS, pH 7.2
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the antibody at -20 °C to -80 °C.
Target Details for MAG
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Target
MAG
(Myelin Associated Glycoprotein (MAG))
Alternative Name
Myelin-Associated Glycoprotein (MAG) (MAG Products )
Synonyms
GMA antibody, S-MAG antibody, SIGLEC-4A antibody, SIGLEC4A antibody, siglec-4 antibody, MAG antibody, Gma antibody, siglec-4a antibody, myelin associated glycoprotein antibody, myelin-associated glycoprotein antibody, MAG antibody, mag antibody, Mag antibody
Background
Myelin-associated glycoprotein (MAG), a member of the immunoglobulin superfamily, is a membrane glycoprotein of 100 kDa, and is thought to be involved in the process of myelination. Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin, Nogo and MAG. MAG has been implicated in the inhibition of nerve regeneration in the CNS.Synonyms: GMA, MAG, Siglec-4a
Gene ID
4099
NCBI Accession
NP_002352
UniProt
P20916
Pathways
Neurotrophin Signaling Pathway
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