FADS1 antibody (AA 1-100)

Catalog No. ABIN782376

Product Details anti-FADS1 Antibody

Target: FADS1 (Fatty Acid Desaturase 1 (FADS1))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FADS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to FADS1.

Purification: Affinity chromatography on Protein A

Immunogen: FADS1 antibody was raised against (NP_037534, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2D9

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0,39 mg/mL

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FADS1

Target: FADS1 (Fatty Acid Desaturase 1 (FADS1))

Abstract: FADS1 Products

Synonyms: D5D antibody, FADS6 antibody, FADSD5 antibody, LLCDL1 antibody, TU12 antibody, D5FAD antibody, 0710001O03Rik antibody, A930006B21Rik antibody, AI317215 antibody, DSD antibody, fatty acid desaturase 1 antibody, FADS1 antibody, LOC483793 antibody, Fads1 antibody

Background: FADS1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3) respectively.Synonyms: D5D, Delta(5) desaturase, Delta(5) fatty acid desaturase, FADS-1, FADSD5, Fatty acid desaturase 1

Gene ID: 3992

NCBI Accession: NP_037534

UniProt: O60427

Pathways: Regulation of Lipid Metabolism by PPARalpha