RND3 antibody (AA 1-245)

Catalog No. ABIN782334

Product Details anti-RND3 Antibody

Target: RND3 (rho Family GTPase 3 (RND3))

Binding Specificity: AA 1-245

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RND3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes RND3 / ARHE.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein A Chromatography

Immunogen: RND3 antibody was raised against RND3 (AAH12513, 1 a.a. ~ 245 a.a) full-length recombinant protein with GST tag.

Clone: 1D2

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2

Handling Advice: Avoid freeze-thaw cycles.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C or -80 °C.

Target Details for RND3

Target: RND3 (rho Family GTPase 3 (RND3))

Alternative Name: RND3 / ARHE (RND3 Products)

Synonyms: ARHE antibody, Rho8 antibody, RhoE antibody, memB antibody, MGC83857 antibody, 2610017M01Rik antibody, AI661404 antibody, Arhe antibody, Rhoe antibody, RHOE antibody, arhe antibody, id:ibd2712 antibody, id:ibd2919 antibody, rho8 antibody, rnd3 antibody, wu:fc39h07 antibody, zgc:73080 antibody, wu:fd06e12 antibody, zgc:92324 antibody, Rho family GTPase 3 antibody, Rho family GTPase 3 L homeolog antibody, Rho family GTPase 3a antibody, Rho family GTPase 3b antibody, RND3 antibody, rnd3.L antibody, Rnd3 antibody, rnd3a antibody, rnd3b antibody

Background: Rho-related GTP-binding protein RhoE, also known as RND3, is a small GTPase of the Ras superfamily that regulate the organization of the actin cytoskeleton in response to extracellular growth factors. RND3 activity leads to a decrease in stress fibers and increased cell migration, at least in part through regulation of the Rho-dependent kinase ROCK1. Also, RND3 has been implicated in inhibition of DNA-damage induced apoptosis and cell cycle arrest.Synonyms: MemB protein, RHO8, RHOE, Rho family GTPase 3, Rho-related GTP-binding protein RhoE

Gene ID: 390

NCBI Accession: NP_005159

UniProt: P61587