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HIPK2 antibody
HIPK2
Reactivity: Human, Rat
WB, IHC (p), EIA
Host: Mouse
Monoclonal
1F10
unconjugated
Product Details anti-HIPK2 Antibody
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Target
See all HIPK2 Antibodies
HIPK2
(Homeodomain Interacting Protein Kinase 2 (HIPK2))
Reactivity
All reactivities for HIPK2 antibodies
Human, Rat
Host
All hosts for HIPK2 antibodies
Mouse
Clonality
All clonalities for HIPK2 antibodies
Monoclonal
Conjugate
All conjugates for HIPK2 antibodies
This HIPK2 antibody is un-conjugated
Application
All applications for HIPK2 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to HIPK2.
Cross-Reactivity (Details)
Species reactivity (expected):Rat. Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogen
HIPK2 antibody was raised against recombinant protein
Clone
1F10
Isotype
IgG2a
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Discover our top product HIPK2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0,5 mg/mL
Buffer
PBS, pH 7.2
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for HIPK2
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Target
HIPK2
(Homeodomain Interacting Protein Kinase 2 (HIPK2))
Alternative Name
HIPK2 (HIPK2 Products )
Synonyms
HIPK2 antibody, cb1009 antibody, si:dkey-16j24.2 antibody, si:dkey-239k7.1 antibody, wu:fk56d12 antibody, pro0593 antibody, MGC146781 antibody, PRO0593 antibody, 1110014O20Rik antibody, B230339E18Rik antibody, Stank antibody, PKM antibody, homeodomain interacting protein kinase 2 antibody, serine/threonine kinase antibody, homeodomain interacting protein kinase 2 L homeolog antibody, HIPK2 antibody, Smp_000720 antibody, hipk2 antibody, hipk2.L antibody, Hipk2 antibody
Background
HIPK2, a nuclear serine/threonine kinase similar to the MNB/DYRK type protein kinases, represses transcription mediated by homeodomain containing transcription factors. HIPK2 is activated by ultraviolet (UV) radiation and selectively phosphorylates p53 to promote p53-dependent gene expression. HIPK2 interacts with various proteins, including members of the p53 family, to regulate cell cycle and apoptosis. Variants of HIPK2 have been observed due to alternative splicing.Synonyms: Homeodomain-interacting protein kinase 2
Gene ID
28996
NCBI Accession
NP_001106710
UniProt
Q9H2X6
Pathways
Cell Division Cycle
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