MMP11 antibody

Catalog No. ABIN781659

Product Details anti-MMP11 Antibody

Target: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Reactivity: Human, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This MMP11 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Monoclonal antibody 5ST-4A9 recognizes Human Stromelysin-3. SL-3 (MMP-11) was originally isolated as a breast cancer associated gene. Antigen Distribution: Specifically expressed in stromal cells of breast carcinomas.

Purification: Affinity Chromatography

Immunogen: Full length recombinant Human Stromelysin-3. Antigen, epitope: The epitope has not been further characterized.

Clone: 5ST-4A9

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore by adding 0.5 mL distilled water

Concentration: 0.5 mg/mL

Buffer: Stock solution contains 0.5 mg/mL IgG, PBS, pH 7.2 with 5 mg/mL BSA as stabilizer and 0.01 % Kathon as a preservative.

Preservative: Kathon CG

Precaution of Use: This product contains Kathon CG a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the lyophilized antibody at 2- 8 °C. Following reconstitution, store at -20 °C.

Target Details for MMP11

Target: MMP11 (Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11))

Alternative Name: MMP-11 (MMP11 Products)

Synonyms: SL-3 antibody, ST3 antibody, STMY3 antibody, Stmy3 antibody, MMP-11 antibody, matrix metallopeptidase 11 antibody, matrix metallopeptidase 11 L homeolog antibody, stromelysin-3 antibody, MMP11 antibody, Mmp11 antibody, mmp11.L antibody, LOC103694874 antibody

Background: The MMP stromelysin-3 shares many similarities with other MMPs but also has several unique properties. It has little expression in adult organs under normal physiological conditions but is upregulated in a number of pathological processes such as tumor invasion and may also be involved in tumor initiation. During mammalian development, ST3 is expressed in many processes involving cell migration and tissue morphogenesis, especially where cell death takes place.Synonyms: MMP11, Matrix metalloproteinase-11, SL-3, ST3, STMY3, Stromelysin-3

Gene ID: 4320

NCBI Accession: NP_005931

UniProt: P24347