FOXO antibody (N-Term)
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- Target See all FOXO Antibodies
- FOXO (Forkhead Box, Sub-Group O (FOXO))
- Binding Specificity
- N-Term
- Reactivity
- Drosophila melanogaster
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FOXO antibody is un-conjugated
- Application
- ELISA, Western Blotting (WB)
- Specificity
- Reacts with the Drosophila melanogaster dFOXO protein
- Purification
- Antiserum
- Immunogen
- Synthetic peptide derived from Nter domain of the Drosophila dFOXO protein.
- Isotype
- IgG
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- Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1:500 - 1:2000) - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Expiry Date
- 24 months
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- Target
- FOXO (Forkhead Box, Sub-Group O (FOXO))
- Alternative Name
- Forkhead Box Protein O (dFOXO) (FOXO Products)
- Synonyms
- 3143 antibody, Afx antibody, CG3143 antibody, Dfoxo antibody, DmQ95V5 antibody, Dmel\\CG3143 antibody, FKHR antibody, FOXO antibody, FoxO antibody, Foxo antibody, Q95V55 antibody, anon-WO0118547.374 antibody, cg3143 antibody, dFOXO antibody, dFoxO antibody, dFoxo antibody, dfoxo antibody, fd88A antibody, foxO antibody, foxo antibody, forkhead box, sub-group O antibody, foxo antibody
- Background
- Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.
- Gene ID
- 41709
- UniProt
- Q95V55
- Pathways
- Cellular Glucan Metabolic Process, Regulation of Cell Size
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