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FOXO antibody (N-Term)

FOXO Reactivity: Drosophila melanogaster ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN780412
  • Target See all FOXO Antibodies
    FOXO (Forkhead Box, Sub-Group O (FOXO))
    Binding Specificity
    N-Term
    Reactivity
    Drosophila melanogaster
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    This FOXO antibody is un-conjugated
    Application
    ELISA, Western Blotting (WB)
    Specificity
    Reacts with the Drosophila melanogaster dFOXO protein
    Purification
    Antiserum
    Immunogen
    Synthetic peptide derived from Nter domain of the Drosophila dFOXO protein.
    Isotype
    IgG
  • Application Notes

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    WB(1:500 - 1:2000)

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Must be reconstituted in distilled water.
    Storage
    4 °C/-20 °C
    Storage Comment
    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    Expiry Date
    24 months
  • Target
    FOXO (Forkhead Box, Sub-Group O (FOXO))
    Alternative Name
    Forkhead Box Protein O (dFOXO) (FOXO Products)
    Synonyms
    3143 antibody, Afx antibody, CG3143 antibody, Dfoxo antibody, DmQ95V5 antibody, Dmel\\CG3143 antibody, FKHR antibody, FOXO antibody, FoxO antibody, Foxo antibody, Q95V55 antibody, anon-WO0118547.374 antibody, cg3143 antibody, dFOXO antibody, dFoxO antibody, dFoxo antibody, dfoxo antibody, fd88A antibody, foxO antibody, foxo antibody, forkhead box, sub-group O antibody, foxo antibody
    Background
    Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.
    Gene ID
    41709
    UniProt
    Q95V55
    Pathways
    Cellular Glucan Metabolic Process, Regulation of Cell Size
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