TET2 antibody (Internal Region)

Catalog No. ABIN768637

Product Details anti-TET2 Antibody

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Binding Specificity: Internal Region

Reactivity: Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This TET2 antibody is un-conjugated

Application: ELISA

Purpose: Tet2 (mouse)

Sequence: QPSLTSAQIN FSQT

Predicted Reactivity: Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Recent

Immunogen: Peptide with sequence C-QPSLTSAQINFSQT, from the internal region of the protein sequence according to NP_001035490.2.

Isotype: IgG

Application Details

Application Notes:

DS WB Results: Preliminary experiments gave an approx 80 kDa band in lysates of cell line NIH3T3 after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 212 kDa according to NP_001035490.2. The 80 kDa band was successfully blocked by incubation with the immunizing peptide. Have any further splice variants/modified forms been reported?

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for TET2

Target: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Alternative Name: Tet2 (TET2 Products)

Synonyms: KIAA1546 antibody, MDS antibody, Ayu17-449 antibody, E130014J05Rik antibody, mKIAA1546 antibody, RGD1311625 antibody, tet methylcytosine dioxygenase 2 antibody, TET2 antibody, Tet2 antibody

Background: Tet2, tet oncogene family member 2, Ayu17-449, E130014J05Rik, MGC37385, mKIAA1546, methylcytosine dioxygenase TET2, probable methylcytosine dioxygenase TET2, tet oncogene 2

Molecular Weight: 80kDa

NCBI Accession: NP_001035490, NP_001333665

Pathways: Warburg Effect