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p73 alpha antibody (AA 301-350)

TP73 alpha Reactivity: Human WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN763106
  • Target See all p73 alpha (TP73 alpha) products
    p73 alpha (TP73 alpha) (Tumor Protein P73 alpha (TP73 alpha))
    Binding Specificity
    • 14
    • 1
    AA 301-350
    Reactivity
    • 17
    • 2
    • 2
    Human
    Host
    • 17
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This p73 alpha antibody is un-conjugated
    Application
    • 15
    • 12
    • 12
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human p73 alpha
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    p73 alpha (TP73 alpha) (Tumor Protein P73 alpha (TP73 alpha))
    Alternative Name
    P73 alpha (TP73 alpha Products)
    Background

    Synonyms: P73 alpha protein, In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis, Tumor protein p73, p53-like transcription factor, p53-related protein, TP73, P73, P73_HUMAN.

    Background: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011].

    Gene ID
    7161
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