TUSC1 antibody (AA 131-212)

Catalog No. ABIN762641

Product Details anti-TUSC1 Antibody

Target: TUSC1 (Tumor Suppressor Candidate 1 (TUSC1))

Binding Specificity: AA 131-212

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUSC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TUSC1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TUSC1 antibody (ABIN762641)

Kanda, Shimizu, Nomoto, Hibino, Oya, Takami, Kobayashi, Yamada, Inokawa, Tanaka, Fujii, Sugimoto, Koike, Fujiwara, Kodera: "Clinical significance of expression and epigenetic profiling of TUSC1 in gastric cancer." in: Journal of surgical oncology, Vol. 110, Issue 2, pp. 136-44, (2014) (PubMed).

Shimizu, Kanda, Nomoto, Oya, Takami, Hibino, Suenaga, Inokawa, Hishida, Takano, Nishikawa, Yamada, Fujii, Nakayama, Sugimoto, Koike, Fujiwara, Kodera: "Identification of intragenic methylation in the TUSC1 gene as a novel prognostic marker of hepatocellular carcinoma." in: Oncology reports, Vol. 31, Issue 3, pp. 1305-13, (2014) (PubMed).

Target Details for TUSC1

Target: TUSC1 (Tumor Suppressor Candidate 1 (TUSC1))

Alternative Name: Tusc1 (TUSC1 Products)

Synonyms: TSG-9 antibody, TSG9 antibody, 2200001D17Rik antibody, tumor suppressor candidate 1 antibody, TUSC1 antibody, Tusc1 antibody

Background:

Synonyms: TSG9, TSG-9, Tumor suppressor candidate gene 1 protein, TUSC1

Background: This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.

Gene ID: 286319

UniProt: Q2TAM9