RNF139 antibody (AA 501-600)

Catalog No. ABIN762371

Product Details anti-RNF139 Antibody

Target: RNF139 (Ring Finger Protein 139 (RNF139))

Binding Specificity: AA 501-600

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF139 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF139

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RNF139

Target: RNF139 (Ring Finger Protein 139 (RNF139))

Alternative Name: Rnf139 (RNF139 Products)

Synonyms: HRCA1 antibody, RCA1 antibody, TRC8 antibody, 4930555P18Rik antibody, zgc:175173 antibody, rnf139 antibody, ring finger protein 139 antibody, ring finger protein 139 S homeolog antibody, RNF139 antibody, Rnf139 antibody, rnf139 antibody, rnf139.S antibody

Background:

Synonyms: HRCA1, RCA1, Ring finger protein 139, TRC8, RN139_HUMAN.

Background: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

Gene ID: 11236