Nitrilase 1 antibody (AA 111-210)

Catalog No. ABIN762086

Product Details anti-Nitrilase 1 Antibody

Target: Nitrilase 1 (NIT1)

Binding Specificity: AA 111-210

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nitrilase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NIT1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Nitrilase 1

Target: Nitrilase 1 (NIT1)

Alternative Name: Nit1 (NIT1 Products)

Synonyms: MGC85476 antibody, zgc:101630 antibody, ZmNIT1 antibody, DDBDRAFT_0217173 antibody, DDBDRAFT_0302491 antibody, DDB_0217173 antibody, DDB_0302491 antibody, AI255805 antibody, ESTM30 antibody, W57327 antibody, A. THALIANA NITRILASE 1 antibody, ATNIT1 antibody, NITI antibody, NITRILE AMINOHYDROLASE antibody, nitrilase 1 antibody, nitrilase 1 S homeolog antibody, nitrilase 1 antibody, nit1.S antibody, nit1 antibody, NIT1 antibody, nit1-2 antibody, Nit1 antibody

Background:

Synonyms: NIT1, NIT1_HUMAN, Nitrilase 1, Nitrilase homolog 1.

Background: Play a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells, this effect is additive to the tumor suppressor activity of FHIT. it is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.

Gene ID: 4817