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Nicastrin antibody (AA 21-120) (Biotin)

NCSTN Reactivity: Mouse WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin

Catalog No. ABIN761803

Datasheet as PDF

Target See all Nicastrin (NCSTN) Antibodies

Nicastrin (NCSTN)
Binding Specificity
14

3

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 21-120
Reactivity
36

31

21

5

5

4

1

1
Mouse
Host
49

2
Rabbit
Compatible Secondaries
Clonality
42

9
Polyclonal
Conjugate
20

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Nicastrin antibody is conjugated to Biotin
Application
37

13

13

8

6

4

4

3

2

2

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Mouse

Predicted Reactivity

Human,Rat,Cow,Pig,Horse,Chicken

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human Nicastrin

Isotype

IgG

Top Product

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anti-Nicastrin (NCSTN) (AA 16-115) antibody
NCSTN Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 429-669) antibody
NCSTN Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 21-120) antibody
NCSTN Reactivity: Mouse WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (C-Term) antibody
NCSTN Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 99-133) antibody
NCSTN Reactivity: Human, Rat WB Host: Rabbit Polyclonal RB53031 unconjugated

anti-Nicastrin (NCSTN) (AA 1-689) antibody
NCSTN Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 16-115) antibody
NCSTN Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1E8 unconjugated

anti-Nicastrin (NCSTN) (AA 420-655) antibody
NCSTN Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (AA 35-534) antibody
NCSTN Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-Nicastrin (NCSTN) (N-Term) antibody
NCSTN Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C for 12 months.

Expiry Date

12 months
Target

Nicastrin (NCSTN)

Alternative Name

Nicastrin (NCSTN Products)

Synonyms

CG7012 antibody, Dmel\\CG7012 antibody, Nct antibody, Nic antibody, S5A antibody, ST96B antibody, agro antibody, dNct antibody, nic antibody, NCSTN antibody, DKFZp469O2418 antibody, APH2 antibody, 9430068N19Rik antibody, AA727311 antibody, Aph2 antibody, D1Dau13e antibody, Kiaa0253 antibody, mKIAA0253 antibody, nicastrin antibody, Nicastrin antibody, NCSTN antibody, nct antibody, ncstn antibody, CpipJ_CPIJ001617 antibody, Ncstn antibody, aph-2 antibody

Background

Synonyms: ATAG1874, Nicastrin, NCSTN, KIAA0253, UNQ1874/PRO4317
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

Gene ID

23385

UniProt

Q92542

Pathways

Notch Signaling, Neurotrophin Signaling Pathway