CD16a, CD16b (AA 131-230) antibody

Catalog No. ABIN761381

Product Details

Target: CD16a, CD16b

Binding Specificity: AA 131-230

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD16a

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References

Ding, Wang, Wang, Yang, Xue: "Expression of Tumor-Associated Macrophage in Progression of Human Glioma." in: Cell biochemistry and biophysics, (2014) (PubMed).

Target Details

Target: CD16a, CD16b

Alternative Name: CD16a/CD16b

Synonyms: CD16 antibody, CD16b antibody, FCG3 antibody, FCGR3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody, Fc fragment of IgG receptor IIIb antibody, FCGR3B antibody

Background:

Synonyms: CD16, FCG3, CD16A, FCGR3, IGFR3, IMD2, FCR-1, FCRIII, FCGRIII, FCRIIIA, Low affinity immunoglobulin gamma Fc region receptor III-A, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, IgG Fc receptor III-2, FCGR3A, FCGR3B, CD16B,

Background: Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.

Gene ID: 2214

UniProt: P08637