GTPBP4 antibody (AA 301-400)

Catalog No. ABIN761126

Product Details anti-GTPBP4 Antibody

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Binding Specificity: AA 301-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTPBP4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GTPBP4

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GTPBP4

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Alternative Name: Gtpbp4 (GTPBP4 Products)

Synonyms: CRFG antibody, NGB antibody, NOG1 antibody, 2610028C09Rik antibody, Crfg antibody, Gtpbp3 antibody, Nog1 antibody, fi28d07 antibody, zgc:55757 antibody, wu:fi28d07 antibody, xgb antibody, GTP binding protein 4 antibody, GTP binding protein 4 L homeolog antibody, GTPBP4 antibody, Gtpbp4 antibody, gtpbp4 antibody, CC1G_14285 antibody, gtpbp4.L antibody

Background:

Synonyms: Chronic renal failure gene protein, CRFG, G protein binding protein CRFG, GTP binding protein 4, NGB, NOG1, Nucleolar GTP binding protein 1, NOG1_HUMAN.

Background: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [Entrez Gene]

Gene ID: 23560