GADD45GIP1 antibody (AA 121-222)
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- Target See all GADD45GIP1 Antibodies
- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
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Binding Specificity
- AA 121-222
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GADD45GIP1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GADD45GIP1
- Isotype
- IgG
- Top Product
- Discover our top product GADD45GIP1 Primary Antibody
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- Application Notes
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
- Alternative Name
- Gadd45gip1 (GADD45GIP1 Products)
- Synonyms
- si:dkey-194e13.6 antibody, CKBBP2 antibody, CRIF1 antibody, PLINP antibody, PLINP-1 antibody, PRG6 antibody, Plinp1 antibody, 2310040G17Rik antibody, AI425883 antibody, Crif1 antibody, growth arrest and DNA-damage-inducible, gamma interacting protein 1 antibody, GADD45G interacting protein 1 antibody, gadd45gip1 antibody, GADD45GIP1 antibody, Gadd45gip1 antibody
- Background
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Synonyms: CKBBP2, CKII beta associating protein, CKII beta binding protein 2, CKII beta-associating protein, CR6 interacting factor 1, CR6-interacting factor 1, CR1, G45IP_HUMAN, Gadd45gip1, growth arrest and DNA damage inducible, gamma interacting protein 1, Growth arrest and DNA damage-inducible proteins-interacting protein 1, p53 responsive gene 6, p53 responsive gene 6 protein, p53-responsive gene 6 protein, Papillomavirus L2 interacting nuclear protein 1, Papillomavirus L2-interacting nuclear protein 1, PLINP 1, PLINP-1, PLINP1, PRG6.
Background: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
- Gene ID
- 90480
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