CASC5 antibody (AA 2251-2342) (Biotin)

Catalog No. ABIN760393

Product Details anti-CASC5 Antibody (Biotin)

Target: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Binding Specificity: AA 2251-2342

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASC5 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CASC5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CASC5

Target: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Alternative Name: CASC5 (CASC5 Products)

Synonyms: AF15Q14 antibody, CT29 antibody, D40 antibody, KNL1 antibody, PPP1R55 antibody, Spc7 antibody, hKNL-1 antibody, hSpc105 antibody, 2310043D08Rik antibody, 5730505K17Rik antibody, Rad51 antibody, kinetochore scaffold 1 antibody, Kinetochore null protein 1 antibody, KNL1 antibody, Knl1 antibody, knl-1 antibody

Background:

Synonyms: Protein D40/AF15q14, AF15Q14, ALL1 fused gene from chromosome 15q14, Blinkin bub linking kinetochore protein, Cancer susceptibility candidate 5, Cancer susceptibility candidate gene 5 protein, Cancer/testis antigen 29, CT29, D40, hKNL 1, hSpc105, KIAA1570, Kinetochore null 1 homolog, Kinetochore null protein 1, KNL1, CASC5_HUMAN.

Background: Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Four known isoforms exist.

Gene ID: 57082

Pathways: Maintenance of Protein Location, Autophagy