FTH1 antibody (AA 1-100)

Catalog No. ABIN759641

Product Details anti-FTH1 Antibody

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Binding Specificity: AA 1-100

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FTH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ferritin heavy chain

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-FTH1 antibody (ABIN759641)

Zhang, Zhao, Chang, Zhang, Chu, Zhang, Liu, Guo, Wang, Gao, Zhang, Chu: "Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis." in: Toxicology and applied pharmacology, Vol. 301, pp. 50-60, (2016) (PubMed).

Target Details for FTH1

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Alternative Name: Ferritin heavy chain (FTH1 Products)

Synonyms: FHC antibody, FTH antibody, FTHL6 antibody, PIG15 antibody, PLIF antibody, apoferritin antibody, ferritin antibody, fhc antibody, fth antibody, fth1 antibody, fthl6 antibody, ftn-2 antibody, pig15 antibody, plif antibody, fth1b antibody, Fth antibody, HFt antibody, MFH antibody, fb06g09 antibody, hm:zeh1145 antibody, wu:fb06g09 antibody, wu:fq18c10 antibody, zeh1145 antibody, ferritin heavy chain 1 antibody, ferritin, heavy polypeptide 1 L homeolog antibody, ferritin, heavy polypeptide 1 S homeolog antibody, ferritin heavy polypeptide 1 antibody, ferritin, heavy polypeptide 1a antibody, ferritin antibody, ferritin, heavy polypeptide 1 antibody, tudor domain containing 9 antibody, ferritin, heavy polypeptide 1 a antibody, FTH1 antibody, fth1.L antibody, fth1.S antibody, Fth1 antibody, fth1a antibody, EAMY_RS19690 antibody, fth1 antibody, TDRD9 antibody

Background:

Synonyms: FHC, FTH, HFE5, PLIF, FTHL6, PIG15, Ferritin heavy chain, Ferritin H subunit, Cell proliferation-inducing gene 15 protein, FTH1, OK/SW-cl.84

Background: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).

Gene ID: 2495

UniProt: P02794

Pathways: Transition Metal Ion Homeostasis