CNTN2 antibody (AA 161-260)

Catalog No. ABIN758726

Product Details anti-CNTN2 Antibody

Target: CNTN2 (Contactin 2 (Axonal) (CNTN2))

Binding Specificity: AA 161-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNTN2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TAG1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CNTN2

Target: CNTN2 (Contactin 2 (Axonal) (CNTN2))

Alternative Name: TAG1 (CNTN2 Products)

Synonyms: tag1 antibody, si:dz37k09.2 antibody, CNTN2 antibody, D130012K04Rik antibody, TAG-1 antibody, Tax antibody, AXT antibody, TAX antibody, TAX1 antibody, AXONIN-1 antibody, TAG-564 antibody, TAG1 antibody, contactin 2 antibody, contactin 2 (axonal) antibody, cntn2 antibody, CNTN2 antibody, Cntn2 antibody

Background:

Synonyms: Axonal glycoprotein TAG 1, Axonal glycoprotein TAG-1, Axonal glycoprotein TAG1, Axonin 1, Axonin-1, Axonin1, AXT, CNTN 2, Cntn2, CNTN2_HUMAN, contactin 2 axonal, Contactin 2, Contactin-2, Contactin2, DKFZp781D102, MGC157722, TAG 1, TAG 564, TAG564, TAX 1, TAX, TAX-1, TAX1, Transient axonal glycoprotein 1, Transiently expressed axonal glycoprotein.

Background: Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.

Gene ID: 6900

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size