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CDC6 antibody (pSer54)

CDC6 Reactivity: Human WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN756997
  • Target See all CDC6 Antibodies
    CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
    Binding Specificity
    • 19
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer54
    Reactivity
    • 94
    • 27
    • 19
    • 4
    • 1
    Human
    Host
    • 83
    • 10
    • 1
    Rabbit
    Clonality
    • 77
    • 17
    Polyclonal
    Conjugate
    • 41
    • 7
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDC6 antibody is un-conjugated
    Application
    • 65
    • 41
    • 24
    • 13
    • 11
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Cdc6 around the phosphorylation site of Ser54 [PL(p-S)PR]
    Isotype
    IgG
    Top Product
    Discover our top product CDC6 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
    Alternative Name
    Cdc6 (CDC6 Products)
    Synonyms
    CDC18L antibody, HsCDC18 antibody, HsCDC6 antibody, cell division cycle 6 antibody, CDC6 antibody, Cdc6 antibody
    Background

    Synonyms: Cell Division Cycle protein 6, Cdc 18L, Cdc 6, CDC18 cell division cycle 18, S.pombe, homolog like, CDC18 S.pombe, CDC18 like, CDC18S.pombe, Cdc18L, CDC6 related protein, Cdc6p, Cell cycle controller, Cell division control protein 6, Cell division control protein 6 homolog, Cell division cycle 18, Cell division cycle 18 homolog, Cell division cycle 6 homolog, Cell division cycle 6 protein, HsCDC 18, HsCDC 6, HsCDC18, HsCDC6, p62, p62cdc 6, p62cdc6, CDC6_HUMAN.

    Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

    Gene ID
    990
    Pathways
    DNA Replication, Synthesis of DNA
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