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SNRPE antibody (pSer446)

SNRPE Reactivity: Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN756787
  • Target See all SNRPE Antibodies
    SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))
    Binding Specificity
    • 15
    • 15
    • 9
    • 9
    • 8
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer446
    Reactivity
    • 75
    • 58
    • 54
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Mouse, Rat
    Host
    • 89
    • 1
    Rabbit
    Clonality
    • 90
    Polyclonal
    Conjugate
    • 29
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SNRPE antibody is un-conjugated
    Application
    • 29
    • 29
    • 27
    • 25
    • 13
    • 12
    • 9
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human B-Raf around the phosphorylation site of Ser446
    Isotype
    IgG
    Top Product
    Discover our top product SNRPE Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))
    Alternative Name
    B-Raf (SNRPE Products)
    Synonyms
    B-raf antibody, HYPT11 antibody, SME antibody, Sm-E antibody, b-raf antibody, sm-e antibody, sme antibody, SmE antibody, snRNP-E antibody, AL022645 antibody, C76690 antibody, zgc:56682 antibody, small nuclear ribonucleoprotein polypeptide E antibody, small nuclear ribonucleoprotein polypeptide E L homeolog antibody, small nuclear ribonucleoprotein E antibody, SNRPE antibody, snrpe.L antibody, Snrpe antibody, snrpe antibody
    Background

    Synonyms: B Raf phospho S446, p-B Raf phospho S446, 94 kDa B raf protein, B raf 1, B Raf proto oncogene serine threonine protein kinase, BRAF 1, Braf, BRAF1, cRmil, MGC126806, MGC138284, Murine sarcoma viral v-raf oncogene homolog B1, Murine sarcoma viral v raf oncogene homolog B1, p94, RAFB 1, RAFB1, v raf murine sarcoma viral oncogene homolog B1, FLJ95109.

    Background: The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.

    Gene ID
    673
    Pathways
    Ribonucleoprotein Complex Subunit Organization, Hepatitis C
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