APC1 antibody (pSer377)

Catalog No. ABIN755932

Product Details anti-APC1 Antibody

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Binding Specificity: pSer377

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APC1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human ANAPC1 around the phosphorylation site of Ser377

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for APC1

Target: APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

Alternative Name: APC1 (ANAPC1 Products)

Synonyms: APC1 antibody, MCPR antibody, TSG24 antibody, DDBDRAFT_0186456 antibody, DDBDRAFT_0234263 antibody, DDB_0186456 antibody, DDB_0234263 antibody, 2610021O03Rik antibody, AI047775 antibody, AI853536 antibody, AW547281 antibody, Apc1 antibody, Mcpr antibody, tsg24 antibody, EMBRYO DEFECTIVE 2771 antibody, MOP10.10 antibody, MOP10_10 antibody, anaphase promoting complex subunit 1 antibody, E3 ubiquitin ligase antibody, ANAPC1 antibody, Anapc1 antibody, CC1G_09696 antibody, anapc1 antibody, EMB2771 antibody

Background:

Synonyms: Apc1 phospho S377, p-Apc1 phospho S377, ANAPC1Ser377, ANAPC 1, ANAPC1, Anaphase promoting complex subunit 1, anaphase-promoting complex 1 meiotic checkpoint regulator, Anaphase-promoting complex subunit 1, Apc 1, APC1, APC1_HUMAN, Cyclosome subunit 1, MCPR, Meiotic checkpoint regulator, Mitotic checkpoint regulator, Protein Tsg 24, Protein Tsg24, Testis-specic gene 24 protein, TSG 24, TSG24.

Background: This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011].

Gene ID: 64682