SGPL1 antibody (AA 301-400)

Catalog No. ABIN755128

Product Details anti-SGPL1 Antibody

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Binding Specificity: AA 301-400

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGPL1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SGPL1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SGPL1 antibody (ABIN755128)

Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: "Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation." in: Nature communications, Vol. 7, pp. 10963, (2016) (PubMed).

Target Details for SGPL1

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Alternative Name: SGPL1 (SGPL1 Products)

Synonyms: SGPL1 antibody, zgc:162153 antibody, AI428538 antibody, D10Xrf456 antibody, S1PL antibody, Spl antibody, SPL antibody, Spgl1 antibody, spl antibody, sphingosine-1-phosphate lyase 1 antibody, sphingosine-1-phosphate lyase 1 L homeolog antibody, sphingosine phosphate lyase 1 antibody, SGPL1 antibody, sgpl1.L antibody, sgpl1 antibody, Sgpl1 antibody

Background:

Synonyms: SPL, S1PL, Sphingosine-1-phosphate lyase 1, SP-lyase 1, SPL 1, hSPL, Sphingosine-1-phosphate aldolase, SGPL1, KIAA1252

Background: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.

Gene ID: 8879

UniProt: O95470

Pathways: Platelet-derived growth Factor Receptor Signaling