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BRIP1 antibody

BRIP1 Reactivity: Human, Mouse, Rat, Chicken, Cow, Dog, Horse, Pig WB, IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN753718
  • Target See all BRIP1 Antibodies
    BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))
    Reactivity
    Human, Mouse, Rat, Chicken, Cow, Dog, Horse, Pig
    Host
    • 54
    • 3
    • 1
    Rabbit
    Clonality
    • 55
    • 3
    Polyclonal
    Conjugate
    • 19
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This BRIP1 antibody is un-conjugated
    Application
    • 43
    • 23
    • 22
    • 13
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus), Rabbit, Cow (Bovine), Pig (Porcine), Horse (Equine), Dog (Canine), Chicken
    Purification
    affinity purified by Protein A
    Immunogen
    Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human BACH1
    Please inquire for sequence information.
    Isotype
    IgG
    Top Product
    Discover our top product BRIP1 Primary Antibody
  • Application Notes
    WB(1:100-500)
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1mg/1ml
    Buffer
    0.01M PBS, pH 7.4 with 10 mg/ml BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))
    Alternative Name
    BACH1/BRIP1 (BRIP1 Products)
    Synonyms
    MGC68622 antibody, BRIP1 antibody, fancj antibody, si:ch211-158l18.1 antibody, BACH1 antibody, FANCJ antibody, OF antibody, 3110009N10Rik antibody, 8030460J03Rik antibody, Bach1 antibody, FACJ antibody, Fancj antibody, BRCA1 interacting protein C-terminal helicase 1 antibody, BRCA1 interacting protein C-terminal helicase 1 L homeolog antibody, Brip1 antibody, brip1.L antibody, BRIP1 antibody, brip1 antibody
    Background
    BACH1 is a member of the DEAH helicase family that interacts with BRCA1 in vivo. BACH1 is a DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. BACH1 acts late in the Fanconi anemia pathway after FANCD2 ubiquitination and is involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. The BACH1/BRCA1 complex formation contributes to a key function of BRCA1. Therefore it is likely that BACH1 is a target of germline cancer-inducing mutations.
    Synonym: BACH 1, BRIP1, BACH-1, BRAC 1 Associated C Terminal Helicase 1, BRCA 1 Interacting Protein 1, BRCA1 binding helicase like protein BACH1, BRCA1 interacting protein C terminal helicase 1, BRIP 1, BRIP-1, FANCJ, ATP dependent RNA helicase BRIP1, Fanconi anemia group J protein, FLJ90232, MGC126521, MGC126523, OF antibody Protein FACJ.
    Molecular Weight
    130kDa
    Gene ID
    571
    Pathways
    DNA Damage Repair
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