GOT1 antibody (AA 301-400)
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- Target See all GOT1 Antibodies
- GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))
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Binding Specificity
- AA 301-400
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GOT1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- This antibody is specific for cytoplasmic Aspartate Aminotransferase, and will not detect the mitochondrial form.
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat,Dog,Cow,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Aspartate aminotransferase, cytoplasmic
- Isotype
- IgG
- Top Product
- Discover our top product GOT1 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))
- Alternative Name
- Aspartate Aminotransferase, Cytoplasmic (GOT1 Products)
- Synonyms
- ASTQTL1 antibody, GIG18 antibody, cAspAT antibody, cCAT antibody, AST antibody, ISSD antibody, NSD antibody, SD antibody, SIALIN antibody, SIASD antibody, SLD antibody, xr406 antibody, CASPAT antibody, ASPARTATE AMINOTRANSFERASE antibody, ATAAT antibody, MATERNAL EFFECT EMBRYO ARREST 17 antibody, MEE17 antibody, T26C19.9 antibody, T26C19_9 antibody, aspartate aminotransferase antibody, aatA antibody, 83.t00021 antibody, AI789014 antibody, Got-1 antibody, Aspat antibody, Gaspat antibody, AL022787 antibody, FABP-pm antibody, Got-2 antibody, mAspAT antibody, ASPATA antibody, glutamic-oxaloacetic transaminase 1 antibody, solute carrier family 17 member 5 antibody, glutamic-oxaloacetic transaminase 1 homeolog antibody, aspartate aminotransferase antibody, glutamic-oxaloacetic transaminase 1, soluble antibody, glutamic-oxaloacetic transaminase 2 antibody, glutamatic-oxaloacetic transaminase 2, mitochondrial antibody, GOT1 antibody, SLC17A5 antibody, got1.S antibody, AAT antibody, aspC antibody, EHI_006080 antibody, AST2 antibody, ast2 antibody, got1 antibody, Got1 antibody, GOT2 antibody, Got2 antibody
- Background
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Synonyms: cCAT, GIG18, cAspAT, ASTQTL1, Aspartate aminotransferase, cytoplasmic, Cysteine aminotransferase, cytoplasmic, Cysteine transaminase, cytoplasmic, Glutamate oxaloacetate transaminase 1, Transaminase A, GOT1
Background: Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
- Gene ID
- 2805
- UniProt
- P17174
- Pathways
- Hepatitis C, Monocarboxylic Acid Catabolic Process, Methionine Biosynthetic Process
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