Glucagon Receptor antibody (PE-Cy5)
-
- Target See all Glucagon Receptor (GCGR) Antibodies
- Glucagon Receptor (GCGR)
-
Reactivity
- Human, Rat, Mouse, Cow, Dog, Chicken, Guinea Pig, Pig
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Glucagon Receptor antibody is conjugated to PE-Cy5
-
Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Dog,Cow,Pig,Chicken,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Glucagon Receptor
- Isotype
- IgG
- Top Product
- Discover our top product GCGR Primary Antibody
-
-
- Application Notes
-
WB(1:100-500)
FCM(1:100-500)
IHC-P(1:100-500)
IF(IHC-P)(1:100-500) - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- Glucagon Receptor (GCGR)
- Alternative Name
- Glucagon Receptor (GCGR Products)
- Synonyms
- GCGR antibody, GGR antibody, GR antibody, glucagon receptor antibody, GCGR antibody, Gcgr antibody
- Background
-
Synonyms: GGR, GL-R, Glucagon receptor, GCGR
Background: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
- Molecular Weight
- 54kDa
- Gene ID
- 2642
- UniProt
- P47871
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
-