HSD3B1 antibody

Catalog No. ABIN750943

Product Details anti-HSD3B1 Antibody

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD3B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSD3B1

Isotype: IgG

Application Details

Application Notes: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HSD3B1

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Alternative Name: Hsd3b1 (HSD3B1 Products)

Synonyms: 3BETAHSD antibody, HSD3B antibody, HSDB3 antibody, HSDB3A antibody, I antibody, SDR11E1 antibody, HSD3B1 antibody, MGC131206 antibody, D3Ertd383e antibody, 3B-HSD antibody, 3BHSD antibody, si:rp71-68n21.10 antibody, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 antibody, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 antibody, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 L homeolog antibody, HSD3B1 antibody, LOC469446 antibody, LOC713091 antibody, hsd3b1.L antibody, LOC100451655 antibody, Hsd3b1 antibody, hsd3b1 antibody

Background:

Synonyms: 3 beta and steroid delta isomerase 1, 3 beta and steroid hydroxy delta 5 steroid dehydrogenase, 3 beta HSD I, 3BH, 3BHSD, HGNC:5217, HSD3B, HSD3B1, HSDB3, HSDB3A, Hydroxy delta 5 steroid dehydrogenase 3 beta and steroid delta isomerase 1, Hydroxy delta 5 steroid dehydrogenase, trophoblast antigen.

Background: HSD3B1 (3-beta hydroxysteroid dehydrogenase) is a bifunctional enzyme that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.There are two HSD3B1 proteins, type I and type II. Expressed by different genes, they function in different areas of the body. HSD3B1 has been shown to be a highly specific and sensitive trophoblast-associated marker.

Gene ID: 3283

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis