Cyclic GMP antibody
cGMP
IF (cc), IF (p), ELISA, IHC (fro), IHC (p)
Host: Rabbit
Polyclonal
unconjugated
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- Target See all Cyclic GMP (cGMP) Antibodies
- Cyclic GMP (cGMP)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Cyclic GMP antibody is un-conjugated
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- Due to the fact that BSA is used as the carrier, this antibody will cross-react with Albumin.
- Cross-Reactivity
- Rat
- Cross-Reactivity (Details)
- cGMP
- Purification
- Purified by Protein A.
- Immunogen
- OVA conjugated cGMP
- Isotype
- IgG
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- Application Notes
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IHC-P 1:100-500
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- Cyclic GMP (cGMP)
- Alternative Name
- Cgmp (cGMP Products)
- Target Type
- Chemical
- Background
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Synonyms: Cyclic GMP, Cyclic guanosine monophosphate, Guanosine 3 5 Cyclic Monophosphate.
Background: Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
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