CENPA antibody (AA 65-140)
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- Target See all CENPA Antibodies
- CENPA (Centromere Protein A (CENPA))
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Binding Specificity
- AA 65-140
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CENPA antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CENPA
- Isotype
- IgG
- Top Product
- Discover our top product CENPA Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- CENPA (Centromere Protein A (CENPA))
- Alternative Name
- CENPA (CENPA Products)
- Background
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Synonyms: CenH3, CENP-A, Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENPA
Background: Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).
- Gene ID
- 1058
- UniProt
- P49450
- Pathways
- Chromatin Binding, Maintenance of Protein Location
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