IL27 Receptor alpha antibody (AA 21-120)

Catalog No. ABIN749498

Product Details anti-IL27 Receptor alpha Antibody

Target: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Binding Specificity: AA 21-120

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL27 Receptor alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-27RA

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-IL27 Receptor alpha antibody (ABIN749498)

Xu, Yi, Wang, Hu, Han, Xue, Zhang, Luan: "IL-27 regulates the adherence, proliferation, and migration of MSCs and enhances their regulatory effects on Th1 and Th2 subset generations." in: Immunologic research, Vol. 65, Issue 4, pp. 903-912, (2017) (PubMed).

Target Details for IL27 Receptor alpha

Target: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Alternative Name: Il-27ra (IL27RA Products)

Synonyms: IL27RA antibody, CRL1 antibody, IL-27RA antibody, IL27R antibody, TCCR antibody, WSX1 antibody, zcytor1 antibody, IL-27R antibody, Tccr antibody, WSX-1 antibody, Wsx1 antibody, interleukin 27 receptor subunit alpha antibody, interleukin-27 receptor subunit alpha antibody, interleukin 27 receptor, alpha antibody, IL27RA antibody, LOC484907 antibody, Il27ra antibody

Background:

Synonyms: CRL1, TCCR, WSX1, IL27R, IL-27RA, zcytor1, Interleukin-27 receptor subunit alpha, IL-27 receptor subunit alpha, IL-27R subunit alpha, IL-27R-alpha, Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor, IL27RA, UNQ296/PRO336

Background: Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.

Gene ID: 9466

UniProt: Q6UWB1

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response