Plexin A1 antibody (AA 901-1000)

Catalog No. ABIN749213

Product Details anti-Plexin A1 Antibody

Target: Plexin A1 (PLXNA1)

Binding Specificity: AA 901-1000

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin A1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Plexin A1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Plexin A1

Target: Plexin A1 (PLXNA1)

Alternative Name: Plexin A1 (PLXNA1 Products)

Synonyms: PLXNA1 antibody, NOV antibody, NOVP antibody, PLEXIN-A1 antibody, PLXN1 antibody, 2600013D04Rik antibody, PlexA1 antibody, Plxn1 antibody, mKIAA4053 antibody, plexin A1 antibody, plexin A1 L homeolog antibody, plexin A1b antibody, PLXNA1 antibody, plxna1.L antibody, plxna1b antibody, plxna1 antibody, Plxna1 antibody

Background:

Synonyms: NOV, NOVP, PLXN1, PLEXIN-A1, Semaphorin receptor NOV, PLXNA1

Background: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).

Gene ID: 5361

UniProt: Q9UIW2

Pathways: Smooth Muscle Cell Migration