TSH antibody (AA 51-138) (Cy5)

Catalog No. ABIN748977

Product Details anti-TSH Antibody (Cy5)

Target: TSH (Thyroid Stimulating Hormone (TSH))

Binding Specificity: AA 51-138

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSH antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSHB

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TSH

Target: TSH (Thyroid Stimulating Hormone (TSH))

Alternative Name: TSH (TSH Products)

Synonyms: CG7665 antibody, DLGR-1 antibody, DLGR1 antibody, Dmel\CG7665 antibody, FSH antibody, FSH-TSH antibody, Fsh antibody, Fsh/CG7665 antibody, LGR1 antibody, LH/CG receptor antibody, RH44949p antibody, TSH antibody, dLGR1 antibody, Leucine-rich repeat-containing G protein-coupled receptor 1 antibody, Lgr1 antibody

Background:

Synonyms: CHNG4, Thyroid stimulating hormone beta subunit, Thyroid stimulating hormone, beta precursor, Thyrotropin beta subunit, TSHB.

Background: Thyroid stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones. TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.

Gene ID: 7252

UniProt: P01222