Leukotriene B4 Receptor/BLT antibody (AA 101-200)

Catalog No. ABIN748628

Product Details anti-Leukotriene B4 Receptor/BLT Antibody

Target: Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

Binding Specificity: AA 101-200

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leukotriene B4 Receptor/BLT antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LTB4-R1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Leukotriene B4 Receptor/BLT antibody (ABIN748628)

Zinn, Sisignano, Kern, Pierre, Tunaru, Jordan, Suo, Treutlein, Angioni, Ferreiros, Leffler, DeBruin, Offermanns, Geisslinger, Scholich: "The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons." in: The Journal of biological chemistry, Vol. 292, Issue 15, pp. 6123-6134, (2017) (PubMed).

Target Details for Leukotriene B4 Receptor/BLT

Target: Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))

Alternative Name: LTB4-R1/BLTR (LTB4R Products)

Synonyms: BLT1 antibody, BLTR antibody, CMKRL1 antibody, GPR16 antibody, LTB4R1 antibody, LTBR1 antibody, P2RY7 antibody, P2Y7 antibody, Ltb4r1 antibody, LTB4R antibody, lt4r1 antibody, Ltb4r antibody, mBLTR antibody, leukotriene B4 receptor antibody, leukotriene B4 receptor-like antibody, Leukotriene B4 receptor 1 antibody, leukotriene B4 receptor 1 antibody, LTB4R antibody, Ltb4r antibody, LOC415617 antibody, lt4r1 antibody, Ltb4r1 antibody

Background:

Synonyms: BLT1, BLTR, P2Y7, GPR16, LTBR1, P2RY7, CMKRL1, LTB4R1, Leukotriene B4 receptor 1, LTB4-R 1, LTB4-R1, Chemoattractant receptor-like 1, G-protein coupled receptor 16, P2Y purinoceptor 7, LTB4R, BLT

Background: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.

Gene ID: 1241

UniProt: Q15722