IL31RA antibody (AA 401-500)

Catalog No. ABIN748283

Product Details anti-IL31RA Antibody

Target: IL31RA (Interleukin 31 Receptor A (IL31RA))

Binding Specificity: AA 401-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL31RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-31RA

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IL31RA

Target: IL31RA (Interleukin 31 Receptor A (IL31RA))

Alternative Name: IL-31RA/CRL3 (IL31RA Products)

Background:

Synonyms: Interleukin-31 receptor subunit alpha, interleukin-31 receptor subunit alpha precursor, cytokine receptor NR10, mGLM-R, IL-31RA, zcytoR17, IL-31R-alpha, gp130-like receptor, IL-31R subunit alpha, novel cytokine receptor 10, IL-31 receptor subunit alpha, gp130-like monocyte receptor, interleukin 31RA, class I cytokine receptor, Il31ra, CRL3, CRL 3,GLM-R, Glmr, GPL, NR10, HGLM R, HGLMR, IL 31RA , Interleukin 31 receptor A, MGC125346, PRO21384, Soluble type I cytokine receptor CRL3, IL31R_HUMAN.

Background: IL31RA is related to gp130 (IL6ST, MIM 600694), the common receptor subunit for IL6 (MIM 147620)-type cytokines. Oncostatin M receptor (OSMR, MIM 601743) and IL31RA form the heterodimeric receptor through which IL31 (MIM 609509) signals. Expression of IL31RA and OSMR mRNA is induced in activated monocytes, and both mRNAs are constitutively expressed in epithelial cells (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM].

Gene ID: 133396